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Christine Haller Selected Research

vestronidase alfa

9/2019Individual heat map assessments demonstrate vestronidase alfa treatment response in a highly heterogeneous mucopolysaccharidosis VII study population.
5/2019Correction to: Pharmacokinetic and Pharmacodynamic Modeling to Optimize the Dose of Vestronidase Alfa, an Enzyme Replacement Therapy for Treatment of Patients with Mucopolysaccharidosis Type VII: Results from Three Trials.
1/2019Pharmacokinetic and Pharmacodynamic Modeling to Optimize the Dose of Vestronidase Alfa, an Enzyme Replacement Therapy for Treatment of Patients with Mucopolysaccharidosis Type VII: Results from Three Trials.
1/2018A novel Blind Start study design to investigate vestronidase alfa for mucopolysaccharidosis VII, an ultra-rare genetic disease.

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Christine Haller Research Topics

Disease

4Mucopolysaccharidosis VII (Sly Syndrome)
09/2019 - 01/2018
3Mucopolysaccharidoses
09/2019 - 02/2015
1Narcolepsy
11/2018
1Inborn Genetic Diseases (Disease, Hereditary)
01/2018
1Anaphylaxis (Anaphylactic Shock)
05/2015
1Hypersensitivity (Allergy)
05/2015
1Mucopolysaccharidosis IV (Morquio Syndrome)
05/2015
1Postmenopausal Osteoporosis
10/2013
1Drug-Related Side Effects and Adverse Reactions
06/2010
1Disease Progression
05/2005
1Leukocytosis (Pleocytosis)
05/2005
1Multiple Organ Failure (MODS)
05/2005
1Fever (Fevers)
05/2005
1Lactic Acidosis
05/2005
1Heart Arrest (Cardiac Arrest)
05/2005
1Liver Failure
05/2005
1Hypotension (Low Blood Pressure)
05/2005
1Exanthema (Rash)
01/2003

Drug/Important Bio-Agent (IBA)

4vestronidase alfaIBA
09/2019 - 01/2018
3EnzymesIBA
09/2019 - 05/2015
2GlucuronidaseIBA
09/2019 - 01/2019
2GlycosaminoglycansIBA
01/2019 - 05/2015
2human GALNS proteinIBA
05/2015 - 02/2015
2PoisonsIBA
06/2010 - 05/2005
1AcidsIBA
11/2018
1Sodium Oxybate (gamma Hydroxybutyrate)FDA Link
11/2018
1Immunoglobulin E (IgE)IBA
05/2015
1AntibodiesIBA
05/2015
1Keratan SulfateIBA
05/2015
1Keratins (Keratin)IBA
05/2015
1Sulfates (Sulfates, Inorganic)IBA
05/2015
1DenosumabFDA Link
10/2013
1Yohimbine (Yocon)IBA
06/2010
1ColchicineFDA LinkGeneric
05/2005
1Anti-Bacterial Agents (Antibiotics)IBA
05/2005
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
05/2005
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2003

Therapy/Procedure

2Enzyme Replacement Therapy
05/2019 - 01/2019
1Critical Care (Surgical Intensive Care)
05/2005